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Advanced Center For Cryo-Electron Microscopy Facility

Indian Institute of Science, Bangalore

Publications

  • Sengupta, N., Mondal, A. K., Mishra, S., Chattopadhyay, K., & Dutta, S. (2021). Single-particle cryo-EM reveals conformational variability of the oligomeric VCC β-barrel pore in a lipid bilayer. Journal of Cell Biology, 220(12), e202102035.

  • Pramanick, I., Sengupta, N., Mishra, S., Pandey, S., Girish, N., Das, A., & Dutta, S. (2021). Conformational flexibility and structural variability of SARS-CoV2 S protein. Structure.

  • Kumar, A., Gulati, S., & Dutta, S. (2021). User-friendly, High-throughput, and Fully Automated Data Acquisition Software for Single-particle Cryo-electron Microscopy. Journal of Visualized Experiments: Jove, (173).

  • Simplified Approach for Preparing Graphene Oxide TEM Grids for Stained and Vitrified Biomolecules. Kumar A, Sengupta N, Dutta S.Nanomaterials (Basel). 2021 Mar 5;11(3):643. doi: 10.3390/nano11030643.

  • Malladi SK, Singh R, Pandey S, Gayathri S, Kanjo K, Ahmed S, Khan MS, Kalita P, Girish N, Upadhyaya A, Reddy P, Pramanick I, Bhasin M, Mani S, Bhattacharyya S, Joseph J, Thankamani K, Raj VS, Dutta S, Singh R, Nadig G, Varadarajan R. Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment. J Biol Chem. 2020 Nov 5:jbc.RA120.016284. doi: 10.1074/jbc.RA120.016284.

  • N-Terminal Region of Vibrio parahemolyticus Thermostable Direct Hemolysin Regulates the Membrane-Damaging Action of the Toxin. Kundu N, Verma P, Kumar A, Dhar V, Dutta S, Chattopadhyay K.Biochemistry. 2020 Feb 4;59(4):605-614. doi: 10.1021/acs.biochem.9b00937. Epub 2019 Dec 20.

  • Tyrosine in the hinge region of the pore-forming motif regulates oligomeric β-barrel pore formation by Vibrio cholerae cytolysin. Mondal AK, Verma P, Sengupta N, Dutta S, Bhushan Pandit S, Chattopadhyay K.Mol Microbiol. 2020 Oct 21. doi: 10.1111/mmi.14631. Online ahead of print.

  • Malladia SK, Schreiberb D, Pramanicka I, Sridevia MA, Goldenzweigb A, Dutta S, Fleishman SJ, Varadarajan R. One-step sequence and structure-guided optimization of HIV-1 envelope gp140. Current Research in Structural Biology. 2020 Volume 2, Pages 45-55. https://doi.org/10.1016/j.crstbi.2020.04.001.

  • Kundu N ,Verma P ,Kumar A , Dhar V, Dutta S, Chattopadhyay K, N-Terminal Region of Vibrio parahemolyticus Thermostable Direct Hemolysin Regulates the Membrane-Damaging Action of the Toxin. Biochemistry. 2020 Feb 4;59(4):605-614. doi: 10.1021/acs.biochem.9b00937.

  • Ghosh E, Dwivedi H, Baidya M, Srivastava A, Kumari P, Stepniewski T, Kim HR, Lee MH, van Gastel J, Chaturvedi M, Roy D, Pandey S, Maharana J, Guixà-González R, Luttrell LM, Chung KY, Dutta S, Selent J, Shukla AK. Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms. Cell Rep. 2019 Sep 24;28(13):3287-3299.e6. doi: 10.1016/j.celrep.2019.08.053

  • Datta M, Aroli S, Karmakar K, Dutta S, Chakravortty D, Varshney U. Development of mCherry tagged UdgX as a highly sensitive molecular probe for specific detection of uracils in DNA. Biochem Biophys Res Commun. 2019 Oct 8;518(1):38-43. doi: 10.1016/j.bbrc.2019.08.005. Epub 2019 Aug 9.

  • Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laermans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, Skiniotis G, Kobilka BK. Structural insights into the activation of metabotropic glutamate receptors. Nature. 2019 Feb;566(7742):79-84.

  • Bhandari S, Biswas S, Chaudhary A, Dutta S, Suguna K. Dodecameric structure of a small heat shock protein from Mycobacterium marinum M. Proteins. 2019 Jan 11. doi: 10.1002/prot.25657.

  • Kumar S, Panda H, Makhdoomi MA, Mishra N, Safdari HA, Chawla H, Aggarwal H, Reddy ES, Lodha R, Kumar Kabra S, Chandele A, Dutta S, Luthra K. An HIV-1 broadly neutralizing antibody from a clade C infected pediatric elite neutralizer potently neutralizes the contemporaneous and autologous evolving viruses. J Virol. 2018 Nov 14. pii: JVI.01495-18. doi: 10.1128/JVI.01495-18.

  • Safdari, HA, Pandey, S, Shukla, AK, Dutta, S. (2018) Illuminating GPCR Signaling by Cryo-EM. Trends Cell Biol, 28, 591-594. (Corresponding Author)
  • Kesavardhana S, Das R, Datta CM, Ecto R, Srilatha L, DiStefano NS, Swoyer RD, Joyce JG, Dutta S et al. Structure-based Design of Cyclically Permuted HIV-1 gp120 Trimers That Elicit Neutralizing Antibodies. J Biol Chem, 2017, 292, 278-291.