RESEARCH INTERESTS

We are interested both in a basic understanding of protein packing, folding and stability as well as application of this knowledge to address biologically relevant problems. We study a large number of systems ranging from small, stable, globular proteins to complex viral glycoproteins.

Current areas of focus include:

·         Immunogen design for viral vaccines

·         Insights into protein structure and stability from saturation mutagenesis

·         Computational studies of protein packing and stability