Sagar Chittori |
Contact | c/o M.R.N. Murthy Molecular Biophysics Unit Indian Institute of Science Bangalore - 560 012 India
| Tel : +91 80 2293 2458 Mobile: +91 9986 527 286 Fax: +91 80 2360 0535 E-mail: sagar@mbu.iisc.ernet.in http://iisc.academia.edu/SagarChittori |
|
Education
Doctor of Philosophy (2006-present), Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India
Master of Science (2003-2006) in Biological Sciences, Indian Institute of Science, Bangalore, India
Bachelor of Science (2000-2003) in Biochemistry, Deshbandhu college, Delhi University, New Delhi, India
Membership of professional societies
Indian Biophysical Society (IBS)
Awards
Senior Research Fellowship (2008-2010) by Council for Scientific and Industrial Research (CSIR)
Joint CSIR-UGC Junior Research Fellowship (2006-2008) and Eligibility for Lectureship-National Eligibility Test (NET)
Travel support prize for the poster entitled "Metabolic adaptation for short-chain fatty acids degradation: crystal structure of 2-methylcitrate synthase from Salmonella typhimurium" at 10th Conference of Asian Crystallographic Association held during October 31st-November 3rd, 2010 at BEXCo, Busan, Korea
Symposia, workshops and conferences
Poster presentation "Metabolic adaptation for short-chain fatty acids degradation: crystal structure of 2-methylcitrate synthase from Salmonella typhimurium" at 10th Conference of Asian Crystallographic Association held during October 31st-November 3rd, 2010 at BEXCo, Busan, Korea
Invited lecture 'e-Lecture' Workshop on Genomics and Proteomics held during August 17th-18th, 2010 at Sri Padmavathi Mahila Visvavidyalayam, Tirupati, India
Participation 5th International conference on Bioinformatics and Biotechnology (InCoB) held during December 18th-20th, 2006 at The Ashok, New Delhi, India
Participation 35th National Seminar on Crystallography held during February 22nd-24th, 2006 at National Physical Laboratory, New Delhi, India
Poster presentation “Structure of a putative mutarotase YeaD from Salmonella typhimurium: comparison with galactose mutarotases” at International Symposium on Recent Trends in Macromolecular Structure and Function, January 18th-20th, 2006, Department of Crystallography and Biophysics, University of Madras, Chennai, India
Participation Symposium on Macromolecular Crystallography, November 15th-6th 2005, CDFD, Gandipeet campus, Hyderabad, India
Participation CCP4 workshop on Computational Crystallography, during March 15th-20th, 2005 and February 18th-22th, 2008, Molecular Biophysics Unit, Indian Institute of Science, Bangalore.
Salient research achievements
* Metabolic adaptation for
utilization of short-chain fatty acids in Salmonella typhimurium:
structural and functional studies on 2-methylcitrate synthase, acetate
and propionate
kinases
(Ph.D. thesis)
* Structural and
biochemical studies on a putative mutarotase (YeaD) from Salmonella
typhimurium (M.S. thesis)
* Molecular
characterization of Viral Protein genome-linked (VPg) of Pepper Vein
Banding Virus (Integrated Ph.D. project)
Skills
Macromolecular Crystallography
Structural visualization and analysis
Bioinformatics analysis
Molecular dynamics and docking
Molecular biology techniques
Biochemical and biophysical characterization
Enzyme kinetics
Publications
Chittori S, Savithri HS & Murthy MR. Structural insights into the biochemical specificity and catalytic mechanism of propionate kinase isoforms (PduW and TdcD) of Salmonella typhimurium. (manuscript under preparation)
Chittori S, Savithri HS & Murthy MR. Structural insights into the biochemical specificity and plausible regulation of Salmonella typhimurium acetate kinase. (manuscript submitted)
Chittori S, Savithri HS, Murthy MR (2011). Crystal structure of Salmonella typhimurium 2-methylcitrate synthase: insights on domain movement and substrate specificity. J Struct Biol 174, 58-68
Chittori S, Simanshu DK, Savithri HS, Murthy MR (2010). Preliminary X-ray crystallographic analysis of 2-methylcitrate synthase from Salmonella typhimurium. Acta Cryst F66, 467-470
Simanshu DK, Chittori S, Savithri HS, Murthy MR (2007). Structure and function of enzymes involved in the anaerobic degradation of L-threonine to propionate. J Biosci 32, 1195-1206. (Review)
Chittori S, Simanshu DK, Savithri HS, Murthy MR (2007). Structure of the putative mutarotase YeaD from Salmonella typhimurium: structural comparison with galactose mutarotases. Acta Cryst D63, 197-205
Simanshu DK, Chittori S, Savithri HS, Murthy MR (2006). Crystallization and preliminary X-ray crystallographic analysis of biodegradative threonine deaminase (TdcB) from Salmonella typhimurium. Acta Cryst F62, 275-278
Anindya R, Chittori S, Savithri HS (2005). Tyrosine 66 of Pepper vein banding virus genome-linked protein is uridylylated by RNA-dependent RNA polymerase. Virology 336, 154-162